Sectors /

Health & PharmaTech

Shaping the next generation of health and pharmatech

The world just got equipped with fresh AI tooling that can make sense of the seas of data flowing out of healthcare. We see huge opportunities in data infrastructure and unique analytics and AI solutions for healthcare.

Matt Loper

CEO

“Every venture fund I’ve ever met has promised to add value beyond capital, but SignalFire is the first I’ve known to exceed all expectations.”*

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Recent posts

August 11, 2026

Why we invested in Flagler: The AI-native MSK operating system

SignalFire is doubling down on Flagler Health's $50M Series B. Learn how this AI-native MSK operating system is transforming musculoskeletal care for clinics.

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February 10, 2026

Why we invested in Solace: Making healthcare advocacy a standard of care

SignalFire is doubling down on Solace’s $130 million Series C. Discover how Solace uses a full-stack OS and CMS reimbursement (CHI/PIN codes) to turn healthcare advocacy into essential infrastructure, achieving 10x YoY growth and a $1 billion+ valuation.

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October 7, 2025

Why we invested in Peer AI’s agentic backbone for the next era of drug approvals

SignalFire backs Peer AI, an agentic AI platform that accelerates life-sciences regulatory writing, reduces errors, and speeds therapies to patients.

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*Portfolio company founders listed above have not received any compensation for this feedback and may or may not have invested in a SignalFire fund. These founders may or may not serve as Affiliate Advisors, Retained Advisors, or consultants to provide their expertise on a formal or ad hoc basis. They are not employed by SignalFire and do not provide investment advisory services to clients on behalf of SignalFire. Please refer to our disclosures page for additional disclosures.